Description
Section 1. Introduction Introduction to the Handbook on Fear and Anxiety Robert Blanchard, D. Caroline Blanchard, Guy Griebel and David Nutt Section 2. Animal models of Anxiety, Fear and Defense Theoretical approaches to the modeling of anxiety in animals Neil McNaughton and Hlio Zangrossi Jr., The use of conditioning tasks to model fear and anxiety Michael S. Fanselow and Ravikumar Ponnusamy Extinction of fear: from animal studies to clinical interventions Karyn M. Myers and Michael Davis Defensive behaviors, fear and anxiety D. Caroline Blanchard and Robert Blanchard Unconditioned models of fear and anxiety Yoav Litvin, Nathan S. Pentkowski, Roger L. Pobbe, D. Caroline Blanchard and Robert J. Blanchard Section 3. Neural Systems for Anxiety, Fear, and Defense Brain mechanisms of Pavlovian and instrumental aversive conditioning Christopher K. Cain and Joseph E. LeDoux Neural systems activated in response to predators and partial predator stimuli Newton Sabino Canteras A behavioral and neural systems comparison of unconditioned and conditioned defensive behavior Newton S. Canteras and D. Caroline Blanchard Section 4. The Pharmacology of Anxiety, Fear, and Defense Peptide receptor ligands to treat anxiety disorders Thomas Steckler Subtype-selective GABAA/benzodiazepine receptor ligands for the treatment of anxiety disorders James K. Rowlett Modulation of anxiety behaviors by 5-HT-interacting drugs Francisco Silveira Guimares, Antonio Pdua Carobrez and Frederico Guilherme Graeff The glutamatergic system as a potential therapeutic target for the treatment of anxiety disorders John F. Cryan and Kumlesh K. Dev The endocannabinoid system and anxiety responses Marco Bortolato and Daniele Piomelli Genetic factors underlying anxiety-behaviour: a meta-analysis of rodent studies involving targeted mutations of neurotransmission genes Catherine Belzung, Samuel Leman and Guy Griebel The pharmacology of anxiolysis Andrew Holmes Section 5. Handbook of Fear and Anxiety: Clinical and Experimental Considerations Phenomenology of anxiety disorders David J. Nutt, Berta Garcia de Miguel and Simon J.C. Davies How effective are current drug treatments for anxiety disorders, and how could they be improved? David S. Baldwin and Matthew J. Garner Experimental models: panic and fear Gabriel Esquivel, Koen Schruers and Eric Griez Principles and findings from human imaging of anxiety disorders Andrea L. Malizia and David Nutt Stress hormones and anxiety disorders Elizabeth A. Young, James L. Abelson and Israel Liberzon The genetics of human anxiety disorders Eduard Maron, John M. Hettema and Jakov Shlik
