Description
This book is a compilation of past and recent knowledge in the field of emerging drug resistance. The book covers major aspects of drug resistance in bacteria, fungi, malaria, and cancer. Human survival on earth is constantly threatened by disease and syndrome. From the early days, the aim of research in medicine was to find therapeutic agents that can improve the quality of human life. Although humans are dependent on natural compounds from early days their dependence of drugs increased excessively in last century. The advances in chemistry and biology have helped researchers to identify the drugs that have improved treatment of many diseases. The primary factor for treatment of these diseases is dependent on the efficacy of drugs available. The development of resistance to these drugs is one of the major hindrances. Although there are number of books available on this topic, “drug resistance” biology across kingdoms has never been discussed in a coherent way. Dr. Vipin Chandra Kalia is presently working as Chief Scientist, and is the Deputy Director, at Microbial Biotechnology and Genomics, CSIR-Institute of Genomics and Integrative Biology, Delhi. He is a Professor, AcSIR, who obtained his M.Sc. and Ph.D. in Genetics, from Indian Agricultural Research Institute, New Delhi. He has been elected as: (1) Fellow of the National Academy of Sciences (FNASc), (2) Fellow of the National Academy of Agricultural Sciences (FNAAS), and (3) Fellow of the Association of Microbiologists of India (FAMI). His main areas of research are Microbial biodiversity, Bioenergy, Biopolymers, Genomics, Microbial evolution, Quorum sensing, Quorum quenching, Drug discovery and Antimicrobials. He has published 99 papers in Scientic journals such as (1) Nature Biotechnology, (2) Biotechnology Advances, (3) Trends in Biotechnology, (4) Annual Review of Microbiology, (5) Critical Reviews in Microbiology, (6) Bioresource Technology, (7) PLoS ONE, (8) BMC Genomics, (9) International Journal of Hydrogen Energy, and (10) Gene. He has authored 14 book chapters. His works have been cited 3267 times with an h index of 31 and an i10 index of 59. He has Edited 3 books: (i) Quorum Sensing vs Quorum Quenching: A Battle with No End in Sight (2015), (ii) Microbial Factories Vol. 1: Biofuels, Waste treatment (2015) and (iii) Microbial Factories Vol. 2: Biodiversity, Biopolymers, Bioactive Molecules (2015). He is presently the Editor-in-Chief of the Indian Journal of Microbiology and editor of: (1) Journal of Microbiology & Biotechnology (Korea), (2) International Scholarly Res. Network Renewable Energy, (3) Dataset Papers in Microbiology, and (4) PLoS ONE. He is a life member of the following Scientic societies: (1) Society of Biological Chemists of India (2) Society for Plant Biochemistry and Biotechnology, India; (3) Association of Microbiologists of India; (4) Indian Science Congress Association; (5) BioEnergy Society of India, and (6) the Biotech Research Society of India (BRSI). He is also a member of the American Society for Microbiology. Emerging themes in drug resistance Gunjan Arora, Ankur Kulshreshtha, Kriti Arora, Puneet Talwar, Rishi Raj, Gurpreet Grewal, Ritushree Kukreti, Andaleeb Sajid Molecular Mechanism of Drug Resistance: Common Themes C. M. Santosh Kumar Diversity and evolution of microbial drug resistance Shilpa Ray, Susmita Das, Mrutyunjay Suar Functional Roles of Highly Conserved Amino Acid Sequence Motifs A and C in Solute Transporters of the Major Facilitator Superfamily Prathusha Kakarla, Ranjana KC, Ugina Shrestha, Indrika Ranaweera, Mun Mun Mukherjee, T. Mark Willmon, Alberto J. Hernandez, Sharla R. Barr, and Manuel F. Varela How pathogens survive drug pressure? Brijendra Kumar Tiwari*, Gunjan Kak, Deepika Sharma, Krishnamurthy Natarajan Functional diversity and applications of mobile group II introns Bhagwan Rekadwad, Juan M Gonzalez, and Chandrahasya N. Khobragade Bacterial resistance against antibiotics Anil Kumar and Nikita Chordia Drug-resistant tuberculosis Lili Liang, Yun Ma, Xin liu, Yamin Lv Emergence of drug resistance in Mycobacterium and other bacterial pathogens – the post translational modification perspective Manu Kandpal, Suruchi Aggarwal, Shilpa Jamwal, Amit Kumar Yadav Glycogen as Key Energy Storehouse and Possibly Responsible for Multi-Drug Resistance in Mycobacterium Tuberculosis Anil Kumar Gupta, Amit Singh, Sarman Singh Role of external and environmental factors in drug resistance emergence: gut microbiota Daniel Ryan, Sangeeta Jaiswal, Mrutyunjay Suar Efflux mediated drug resistance in Staphylococcus aureus Nitin Pal Kalia Tackling the Antibiotic Resistance: The “Gut” Feeling Richa Misra, Abhijit Maji, Richa Virmani, and Darshan Dhakan In silico analytical tools for Phylogenetic and Functional Bacterial Genomics Vipin Chandra Kalia*, Ravi Kumar, Shikha Koul Exploiting bacterial genomes to develop biomarkers for identification Ravi Kumar, Shikha Koul, Vipin Chandra Kalia Human Fungal Pathogens and Drug Resistance Against Azole Drugs Preetida J. Bhetariya, Neha Sharma, Pragati Singh, Priyanka Tripathi, Santosh K. Upadhyay, and Poonam Gautam Drug Resistance in Malaria C. M. Santosh Kumar Drug Resistance in Cancer Santosh K. Upadhyay, Ramesh C. Rai, Rekha Gehtori, Ashutosh Paliwal, Poonam Gautam, and Penny Joshi BCL2 Family Proteins and Other Role in Cancer Resistance Hamida Thakur and Abid R. Mattoo Perturbed signaling and role of post translational modifications in cancer drug resistance Suruchi Aggarwal, Manu Kandpal, Shailendra Asthana, Amit Kumar Yadav Ovarian Cancer and Resistance to Therapies: Clinical and Laboratory Perspectives Riyaz Basha, Zainab Mohiuddin, Abdul Rahim, Sarfraz Ahmad Initiatives across countries to reduce antibiotic utilization and resistance patterns; impact and implications Brian Godman, Joseph Fadare, Dan Kibuule, Lyna Irawati, Mwangana Mubita, OlayinkaOgunleye, Margaret Oluka, Bene D Anand Paramadhas, Juliana de Oliveira Costa, Lvia Lovato Pires de Lemos, Augusto Afonso Guerra Jnior, Alian A Alrasheedy, Mohamed Azmi Hassali, Fahad Saleem, Thu Huong, and Ilse Truter In silico approaches towards combating antibiotic resistance Rahul Shubhra Mandal and Santasabuj Das Synthetic Solutions to Drug Resistance Gunjan Arora, Richa Misra, and Andaleeb Sajid Future of drug discovery Ahmed Kamal, Shalini Nekkanti, Nagula Shankaraiah, Manda Sathish
