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Gene and Cellular Immunotherapy for Cancer (Cancer Drug Discovery and Development)

SKU: 9783030878511

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Gene and Cellular Immunotherapy for Cancer (Cancer Drug Discovery and Development), Zoran M. Pavlovic, 9783030878511

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Part I: Overview 1. The History of Cellular Therapies 2. Basics of Immunity Part II: CAR-T 3. Biology of CAR-T 4. Cell Types Used for CAR-T Generation 5. Combination Therapeutics with CAR-T Cell Therapy 6. Safety Switches Used for Cellular Therapies 7. Off the Shelf CAR-T 8. Manufacturing of CAR-T Cells: the Assembly Line 9. Navigating Regulations in Gene and Cell Immunotherapy 10. Bringing CAR-T to the Clinic 11. CAR-T Cell Complications 12. Mechanisms of Resistance and Relapse after CAR-T Cell Therapy Part III: TIL 13. Tumor Infiltrating Lymphocytes (TIL): From Bench to Bedside Part IV: TCR 14. T-cell Receptor (TCR) Engineered Cells and Their Transition to Clinic Part V: Viral CTLs 15. Viral Cytotoxic T Lymphocytes (CTLs): from Bench to Bedside Part VI: NK Cell 16. Biology of NK Cells and NK Cells in Clinic Part VII: T/NK cell engagers 17. Biology and Clinical Evaluation of T/NK Cell Engagers Part VIII: Logistics 18. Roadmap for Starting an Outpatient Cellular Therapy Program

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