Description
The ambitious goal of this volume is to provide – in chapters written by accomplished scientists and experts in their field – a comprehensive overview of the currently available information related to the therapeutic utility of adult bone marrow-derived cells. With excitement generated almost daily about the possible uses of stem cells to treat human disease, but the controversy surrounding their use still raging, adult bone-marrow derived cells are more readily available, and have a staggering range of uses. Part 1: Basic Principles. Mobilization of Bone Marrow-Derived Progenitors. Role of Endothelial Nitric Oxide in Bone Marrow Derived Progenitor Cell Mobilization. Immune Plasticity of Bone Marrow Derived Mesenchymal Stromal Cells. Bone Marrow-Derived Cells: The Influence of Aging and Cellular Senescence. Involvement of Marrow-Derived Endothelial Cells in Vascularization.- Part 2: Therapeutic Implication and Clinical Experience. Comparison of Intracardiac Cell Transplantation: Autologous Skeletal Myoblasts versus Bone Marrow Cells. Ischemic Tissue Repair by Autologous Bone Marrow-Derived Stem Cells: Scientific Basis and Pre-Clinical Data. Cell Therapy and Gene Therapy using Endothelial Progenitor Cells for Vascular Regeneration.Mesenchymal Stem Cells for Cardiac Regenerative Therapy. Autotransplantation of Bone Marrow-Derived Stem Cells as a Therapy for Neurodegenerative Diseases. Application of Bone Marrow Progenitors in Patients with Liver Insufficiency. The Participation of Mesenchymal Stem Cells (MSC) in Tumor Stroma Formation and Their Application as Targeted-gene Delivery Vehicles.
