Description
Dr. Cheng Hwee Ming graduated from University of Liverpool with a Joint Honors (Biochemistry/Cell Biology, 1980) and PhD (Immunology, 1983). He has taught Physiology at the Universiti Malaya in Kuala Lumpur since 1985. Dr Cheng has an interest in understanding how students think, learn and in helping them unmask misconceptions in Physiology. His academic books include ‘ Thinking Through Physiology ‘ and the Springer’s ‘Physiology Question-based Learning’ title. Dr Cheng is also the initiator of the annual International Physiology Quiz now in its 18th year, each event participated by more than 90 medical schools from over 20 countries. He is married to Gaik Cheng, a general practitioner, and they have two children, Timothy, Ruth and a grandson, Caleb. Dr. Kumar Seluakumaran received his medical degree from University of Malaya in 2002 and his Ph.D from the University of Western Australia in 2007. He has since been working as a senior lecturer at the Department of Physiology, Faculty of Medicine, University of Malaya. He has been teaching neurophysiology to undergraduate and postgraduate students for the past 13 years. His research interest is in the area of auditory neuroscience and he has published peer-reviewed articles related to central auditory neuronal responses, audiology and psychoacoustics. Assoc Prof Dr Mah Kin Kheong graduated from University Malaya in 1985 and later trained as an anaesthetist in Malaysia and Australia, obtaining his Masters in Anaesthesiology from University Malaya in 1992 and his Fellowship from the Australian and New Zealand College of Anaesthetist in 1994. He was inducted as a Fellow in the Academy of Medicine in Malaysia in 2007. He teaches at the Royal College of Medicine Perak, University Kuala Lumpur. He was the Head of Physiology and the current Deputy Dean of the college. He is also a trainer and examiner in the Conjoint Master of Anaesthesia programme in Malaysia. PART 1: GASTROINTESTINAL PHYSIOLOGY Topic 1: Salivary gland: Savilon Topic 2: Oesophageal sphincters: Upper oesophageal sphincter and lower oesophageal sphincter Topic 3: Stomach as an Acid Producer Topic 4: Homeostasis of gastric acid secretion: neurocrine, paracrine and endocrine system, proton pump inhibitors. Alkaline tide Topic 5: Gastric mucosal barrier, Helicobacter pylori Topic 6: Gastric motility: (Migrating Motor Complex, Receptive Relaxation, Accommodation, Retropulsion) Topic 7: Gastric Emptying Topic 8: Gastrointestinal Rhythmic Contractions Electrical Basis: Slow wave potential Topic 9: Migratory Motor Complex (or migrating myoelectric complex), MMC, Motilin Topic 10: Motility: Peristalsis, Segmentation, Haustration and Mass movement Topic 11: Motility: Peristalsis, Segmentation, Haustration and Mass movement Topic 12: Recycling of bile salts: Enterohepatic Circulation (EHC) Topic 13: Intestinal Fluid Handling: Absorption Topic 14: Intestinal Fluid Handling: Secretion Topic 15: Pancreatic Exocrine function: Pancreatic acinar cell in pancreatic secretion, cholecystokinin (CCK), Auto- digestion Topic 16: Pancreatic Exocrine function: Pancreatic ductal cell, CFTR chloride channel. Secretin Topic 17: Carbohydrate Digestion: Small intestine as the site of digestion and absorption for dietary carbohydrate Topic 18: Fat digestion: Bile salt, emulsification, micelles, lipases, chylomicrons Topic 19: Protein Digestion Topic 20: Protein Absorption Topic 21: Defecation Reflex: Parasympathetic defecation reflex, intrinsic myenteric defection reflex PART 2: NEUROPHYSIOLOGY Topic 1: Electrical Properties of Neurons 1. Resting Membrane Potential (RMP) 2. Equilibrium Potential 3. Membrane conductance 4. Action Potential 5. Neuronal excitability 6. Neuronal refractory period 7. Initiation zone 8. Saltatory conduction 9. Firing rate Topic 2: Synaptic transmission 10. Post-synaptic potentials 11. Synaptic delay 12. Summation 13. Neurotransmitter E. Presynaptic inhibition Topic 3: Receptor mechanism 14. Adequate stimulus 15. Stimulus transduction 16. Stimulus coding 17. Adaptation 18. Sensory discrimination (acuity) Topic 4: Motor system 19. Motor neurons 20. Neuromuscular junction 21. Proprioception 22. Spinal reflex 23. Alpha-gamma coactivation
