Description
This book is intended as a scientific resource for cannabinoid researchers carrying out animal and human experiments, and for those who are interested in learning about future directions in cannabinoid research. Additionally, this book may be of value to investigators currently working outside the field of cannabinoid research who have an interest in learning about these compounds and their atypical cannabinoid signalling. This book provides insight into the potential medical application of cannabinoids and their therapeutic development for the treatment of human disease. PART I: Overview of Non-Cannabinoid Receptors Chapter 1: Overview of Non-Classical Cannabinoid Receptors Grzegorz Godlewski and George Kunos Chapter 2: Overview of Non-Cannabinoid Receptors: Chemistry and Modeling Evangelia Kotsikorou and Patricia Reggio PART II: G-Protein Coupled Receptors Chapter 3: GPR55 in the CNS Hui-Chen Lu, Jane E. Lauckner, John W. Huffman, Ken Mackie Chapter 4: The Role of GPR55 in Bone Biology Lauren S. Whyte and Ruth A. Ross Chapter 5: The Role of GPR55 in Cancer Clara Andradas, Mara M Caffarel, Eduardo Prez-Gmez, Manuel Guzmn and Cristina Snchez Chapter 6: GPR18 and NAGly signaling: New members of the endocannabinoid family or distant cousins? Douglas McHugh and Heather B Bradshaw Chapter 7: Cannabinoid Signaling Through Non CB1/Non CB2 GPCR Targets in Microglia Neta Rimmerman, Ewa Kozela, Rivka Levy, Zvi Vogel, Ana Juknat PART III: Ion Channels Chapter 8: Temperature-Sensitive Transient Receptor Potential Channels as Ionotropic Cannabinoid Receptors Vincenzo Di Marzo and Luciano De Petrocellis Chapter 9: Nonpsychoactive Cannabinoid Action on 5-HT3 and Glycine Receptors Li Zhang and Wei Xiong PART IV: Transcription Factors Chapter 10: Peroxisome proliferator-activated receptors and inflammation James Burston and David Kendall Chapter 11: Peroxisome proliferator-activated nuclear receptors (PPAR) and drug addiction Paola Mascia, Gianluigi Tanda, Sevil Yasar, Stephen J. Heishman and Steven R. Goldberg PART V: Conclusions/Therapeutic Potential Chapter 12: Conclusions: Therapeutic Potential of Novel Cannabinoid Receptors Mary Abood, Roger Sorensen and Nephi Stella
