Description
Chapter Titles Introduction to the complexity of cell surface and tissue matrix glycoconjugates Cells of the central nervous system: An overview of their structure and function Synthesis, processing, and function of N-glycans in N-glycoproteins Synthesis of O-linked glycoconjugates in the nervous system Chemistry and function of glycosaminoglycans in the nervous system Structural analysis of oligosaccharides and glycoconjugates using NMR Glycans and carbohydrate-binding/transforming proteins in axon physiology Neurological consequences of congenital disorders of glycosylation Brain O-GlcNAcylation: from molecular mechanisms to clinical phenotype Ganglioside microdomains on cellular and intracellular and membranes regulate neuronal cell fate determination Gangliosides and cell surface ganglioside glycohydrolases in the nervous system Neuronal ganglioside and GSL metabolism in health and disease Cascades of secondary metabolic errors can generate complex pathologies (in LSDs) Gangliosides in neurodegenerative diseases Functional impairment of the nervous system with glycolipid deficiencies Carbohydrates: binding sites and potential drug targets for neural-affecting pathogens Antibodies to glycolipids in Guillain-Barr syndrome, Miller Fisher syndrome and related autoimmune neurological diseases




