Description
This volume covers all aspects of infection by pathogenic Leptospira species, the causative agents of the world’s most widespread zoonosis. Topics include aspects of human and animal leptospirosis as well as detailed analyses of our current knowledge of leptospiral structure and physiology, epidemiology, pathogenesis, genomics, immunity and vaccines. Updates are presented on leptospiral systematics, identification and diagnostics, as well as practical information on culture of Leptospira. Contact information is also provided for Leptospira reference centers. All chapters were written by experts in the field, providing an invaluable reference source for scientists, veterinarians, clinicians and all others with an interest in leptospirosis. History of Leptospirosis and Leptospira Ben Adler Systematics of Leptospiraceae Paul N. Levett Leptospiral Structure, Physiology and Metabolism Caroline E. Cameron Genomics, Proteomics and Genetics of Leptospira Mathieu Picardeau Leptospirosis in Humans David A. Haake and Paul N. Levett Animal Leptospirosis William A. Ellis The Molecular Basis of Leptospiral Pathogenesis Gerald L. Murray The Leptospiral Outer Membrane David A. Haake and Wolfram R. Zckert Host response to Leptospira Infection Richard L. Zuerner Vaccines Against Leptospirosis Ben Adler The Role of Leptospirosis Reference Laboratories Rudy A Hartskeerl and Lee D Smythe




