Description
Advances in the study and understanding of myasthenia gravis have led to the need for the publication of this important new edition. The goal of Myasthenia Gravis and Related Disorders, Second Edition is identical to the first — to provide the clinician and the scientist with a common resource for understanding this complex disorder. This new edition begins with discussions of neuromuscular junction structure and function and follows with updated chapters covering a wide range of topics, such as the acetylcholine receptor, clinical presentation, diagnostic evaluation, and treatment. Importantly, new supplemental chapters have been added; these discuss rigorous clinical assessments of patients for research trials and the epidemiology and genetics of myasthenia gravis. The discussion of the most challenging aspects of myasthenia gravis, its impact on patients’ psychological make-up, has been expanded as well. Myasthenia Gravis and Related Disorders, Second Edition retains the “personal approach” of the authors regarding treatment and is a valuable resource for meeting the many and varied needs of patients with myasthenia gravis. Preface Henry J. Kaminski, MD Chapter 1 Neuromuscular Junction Physiology and Pathophysiology Eroboghene E. Ubogu, MD and Robert L. Ruff, MD, PhD Chapter 2 Acetylcholine Receptor Structure Jon Lindstrom PhD Chapter 3 Immunopathogenesis of Myasthenia Gravis Bianca M. Conti-Fine, MD, Brenda Diethelm-Okita, Norma Ostlie, MS, Wei Wang, MD, PhD and Monica Milani Chapter 4 Epidemiology and Genetics of Myasthenia Gravis Jeremiah W. Lanford, MD and Lawrence H. Phillips, II, MD Chapter 5 Clinical Presentations of Generalized Myasthenia Gravis Jan B.M. Kuks, MD Chapter 6 Ocular Myasthenia Robert B. Daroff, MD and Michael Benatar, MBChB, DPhil Chapter 7 Thymoma-Associated Myasthenia Gravis Philipp Strbel, MD, Wen-Yu Chuang, MD and Alexander Marx, MD Chapter 8 Electrodiagnosis of Neuromuscular Transmission and Related Disorders Bashar Katiriji, MD, FACP Chapter 9 Autoantibody Testing in the Diagnosis and Management of Autoimmune Disorders of Neuromuscular Transmission and Related Diseases Mark A. Agius, MD, David P. Richman, MD and Angela Vincent, MB, FRCPath Chapter 10 Treatment of Myasthenia Gravis Henry J. Kaminski, MD Chapter 11 Neurocritical Care of Myasthenic Crisis J. Americo Fernandes Filho, MD and Jose I Suarez, MD Chapter 12 Thymectomy for Nonthymomatous Myasthenia Gravis Alfred Jaretzki, MD and Joshua R. Sonett, MD Chapter 13 Lambert-Eaton Syndrome Charles M. Harper, Jr., MD and Vanda A. Lennon, MD, PhD Chapter 14 Neuromyotonia and other Hyperexcitability Syndromes Angela Vincent, MB, FRCPath and Ian Hart, PhD, FRCP Chapter 15 Congenital Myasthenic Syndromes David Beeson, PhD Chapter 16 Toxic NeuromuscularTransmission Disorders James Howard, MD Chapter 17 The Impact of Myasthenia Gravis on Mood, Cognitive Function, and Quality of Life Robert H. Paul, PhD, Larry L. Mullins, and James M. Gilchrist Chapter 18 Myasthenia gravis: Classification and Outcome Measurements Gil I. Wolfe and Richard J. Barohn
