Description
Using rodent models, this volume explores the basic neurobiology of the relationship among chronic pain, opioid pharmacology, and addiction. Opioid and Non-Opioid Drug Responding Under States of Chronic Pain: A Timeline Spanning 1980 to Present Day.- Opioid Self-Administration in the Presence of Chronic Pain: Analgesia or Addiction.- The Influence of Pain on Reward Processing: Current Literature and Prospects.- Chronic Pain Stimuli Downregulate Mesolimbic Dopaminergic Transmission: Possible Mechanism of the Suppression of Opioid Reward.- Drug Addiction and Chronic Pain: A Review of Animal Models.- Biopharmaceutical Considerations of Opioid Analgesics in Models of Self-Administration: Review and Summary.- Prenatal Exposure to Opioids.- Opioids in an Evidence-Based World.
