Description
In the last few years, technologies that allow for monitoring and manipulating neuronal networks at a single cell resolution have been rapidly expanding. In Neuronal Network Analysis: Concepts and Experimental Approaches, experts in the field provide an overview of some of the most advanced techniques for the study of neuronal circuits, highlighting current technical limitations and providing a vision of what is yet to come. Broken into six convenient, interdependent section, this volume covers optical approaches, electrophysiological approaches, both in vitro and in vivo, optogenetics, morpho-functional approaches, and neuronal network analysis in humans. As a volume in the Neuromethods series, this work provides the kind of detailed description and implementation advice that is crucial for getting optimal results. Authoritative and cutting-edge, Neuronal Network Analysis: Concepts and Experimental Approaches will be useful for early career neuroscientists, as well as for experienced neuroscientists, by providing a practical framework for studying the brain as an organ while maintaining an appreciation for its cellular diversity. Part I: Optical Approaches 1. Optical Interrogation of Neural Circuits Tycho M. Hoogland and Peter Saggau 2. In Vivo Functional Imaging of the Olfactory Bulb at Single Cell Resolution Stefan Fink, Yury Kovalchuk, Ryota Homma, Bernd Schwendele, Stephan Direnberger, Lawrence B. Cohen, Oliver Griesbeck, and Olga Garaschuk 3. Two-Photon Imaging of Neural Activity in Awake, Head-Fixed Mice Martin Wienisch, David Blauvelt, Tomokazu F. Sato, and Venkatesh N. Murthy 4. Spatial Light Modulators for Complex Spatio-Temporal Illumination of Neuronal Networks Francesco Difato, Marco Dal Maschio, Riccardo Beltramo, Axel Blau, Fabio Benfenati, and Tommaso Fellin 5. Voltage-Sensitive Dye Imaging of Cortical Function In Vivo Eugene F. Civillico Part II: Electrophysiological Approaches In Vitro 6. An Introduction to In Vitro Slice Approaches for the Study of Neuronal Circuitry Carmen Varela, Daniel A. Llano, and Brian B. Theyel 7. Extracellular Recordings of Synaptic Plasticity and Network Oscillations in Hippocampal Slices Gaga Kochlamazashvili, Oleg Senkov, and Alexander Dityatev 8. Use of Dynamic-Clamp as a Tool to Reveal the Computational Properties of Single Neurons Embedded in Cortical Circuits Alberto Bacci, Antonio Pazienti, and Michele Giugliano 9. Fast Perfusion Methods for the Study of Ligand-Gated Ion Channels Andrea Barberis Part III: Electrophysiological Approaches In Vivo 10. Electrophysiological Approaches for Studying Neuronal Circuits In Vivo George Dragoi 11. Determination of Cortical Circuit Function Using Current Source-Density (CSD) Analysis In Vivo Michael J. Higley 12. Intracellular Whole-Cell Patch-Clamp Recordings of Cortical Neurons in Awake Head-Restrained Mice Sylvain Crochet 13. Investigating Sleep Homeostasis with Extracellular Recording of Multiunit Activity from the Neocortex in Freely-Behaving Rats Vladyslav V. Vyazovskiy, Umberto Olcese, and Giulio Tononi 14. Analysis of Hippocampal Memory Replay Using Neural Population Decoding Fabian Kloosterman 15. High Speed Videography of Embodied Active Sensing in the Rodent Whisker System Jason T. Ritt Part IV: Optogenetics 16. Light-Activated Ion Pumps and Channels for Temporally-Precise Optical Control of Activity in Genetically-Targeted Neurons Brian Y. Chow, Xue Han, Jacob G. Bernstein, Patrick E. Monahan, and Edward S. Boyden 17. Integrated Optogenetic and Electrophysiological Dissection of Local Cortical Circuits In Vivo Jessica A. Cardin 18. Combining Optical Stimulation with Extracellular Electrophysiology in Behaving Mice Joshua H. Siegle Part V: Morpho-Functional Approaches 19. Morphological Approaches to the Anatomical Dissection of Neuronal Circuits David C. Lyon 20. The Isotropic Fractionator: A Fast, Reliable Method to Determine Numbers of Cells in the Brain or Other Tissues Suzana Herculano-Houzel 21. Morpho-Functional Mapping of Cortical Networks in Brain Slice Preparations Using Paired Electrophysiological Recordings Gabriele Radnikow, Robert Heinz Gnter, Manuel Marx, and Dirk Feldmeyer Part VI: Neuronal Network Analysis in Humans 22. Combining Transcranial Magnetic Stimulation with Electroencephalography to Study Human Cortical Excitability and Effective Connectivity Mario Rosanova, Silvia Casarotto, Andrea Pigorini, Paola Canali, Adenauer G. Casali, and Marcello Massimini 23. Biophysically Principled Computational Neural Network Modeling of Magneto-/Electro-Encephalography (MEG/EEG) Measured Human Brain Oscillations Stephanie R. Jones
