Description
Advances in Nitric Oxide and Cancer is a volume that serves to give the latest research on nitric oxide (NO) and cancer. More specifically, the volume reviews significant advances in the application of NO-mediated drugs. The volume explores nitric oxide and its relationship to cancer spanning from its roles in the pathogenesis, prognosis, gene and protein modifications, regulation of resistance to cytotoxics, and therapeutic applications. With chapters written by leading experts, the volume addresses the burgeoning interest in a rapidly advancing field and provides a valuable resource to scientists who have initiated research as well as clinical investigations in their laboratories on the various roles of NO and cancer. Dr. Benjamin Bonavida is a professor at UCLA’s David Geffen School of Medicine for the Department of Microbiology, Immunology, & Molecular Genetics. His other appointments include being a member of the Department of Defense Congressionally Directed Medical Research Program, Member of the National Cancer Institute’s SPORE Program, member of the International Scientific Advisory Board of the Israel Cancer Research Foundation, to name a few. He’s currently a scientific reviewer for several journals and a member of editorial boards including Journal of Clinical Immunology, International Journal of Oncology, and Cancer Biotherapy & Radiopharmaceuticals. Part I: Molecular Cell Signaling by NO in cancer 1. Inflammation-associated Carcinogenesis Involved Interaction Between with iNOS/NO and WNT/beta-catenin Qiang Du and David A. Geller 2. NO and Genomic Stability Vasily A. Yakovlev 3. Targeting Hyponitroxia in Cancer Therapy Bryan Oronsky, Neil Oronsky, Michelle Lybeck, Gary Fanger, Jan Scicinski 4. Mechanism of NO-dependent Regulation of Invasion and Metastasis Aideen E Ryan, Amy J Burke, Francis J Giles, Francis J Sullivan, Sharon A Glynn 5. NO Role in Protumorigenesis and Hypoxia Lynne-Marie Postovit Part II: S-nitrosylation and cancer 6. Impacts of S-nitrosylation in Cancer Tysha N. Medeiros, Dana M. Jarigese, Melissa A. Edwards and Mark A. Brown 7. S-nitrosylation of Cancer Cells Ali Bettaieb, Stphanie Plenchette, Catherine Paul, Vronique Laurens, Sabrina Romagny, Jean-Franois Jeannin 8. Role of S-nitrosylation in Cancer Metastasis Sudjit Luanpitpong and Yon Rojanasakul Part III: Modulation of anti-tumor immune responses by NO 9. NO Immunity and Cancer Hermes J. Garbn 10. Regulation of Anti-tumor Responses by NO Peter Siesj 11. NO Immune Modulation and Tumor Growth Naveena B. Janakiram and Chinthalapally V. Rao Part IV: Therapeutics and overcoming resistance 12. Role of NO in Chemo-immune Resistance Benjamin Bonavida 13. Emerging Role of NO-mediated Therapeutics Cian M. McCrudden and Helen O. McCarthy 14. PDT and NO Emilia Della Pietra and Valentina Rapozzi 15. Regulation of Cell Death by NO Jordi Muntan, Francisco Gallardo-Chamizo, Sheila Pereira, ngela M. De los Santos, ngeles Rodrguez-Hernndez, Lus M. Marn, Jose M. lamo, Francisco J Padillo 16. Discovery and Development of RRx-001 Jan Scicinski, Bryan Oronsky, Shoucheng Ning, Gary R Fanger, Susan J Knox, Mark Bednarski Part V: NO Meditated Alterations in Gene Products 17. Nitric Oxide Coagulation and Cancer Benjamin A. Derman, Hau C. Kwaan, Malak Elbatarny, Maha Othman 18. Neutrosphyngomyelinase 2 Bei Lei Sun and Bulent Mutus
