Description
Alzheimer’s disease is the most prevalent form of dementia. Although it was discovered about a century ago, the first drugs applied in treatment were only introduced in therapy in the last 30 years. This book focuses on the clinical pharmacology of drugs that aim to delay the progression of Alzheimer’s disease, such as anticholinesterases and glutamate receptor antagonists, as well as treatment for the behavioral changes caused by the progression of the disease: antidepressants, antipsychotics, anxiolytics, and mood stabilizers. In addition, it describes important information about the pathophysiology and diagnostic methods of Alzheimer’s disease, emergency situations conditioned by the dementia process, and presents new perspectives for the treatment of Alzheimer’s disease. The ten chapters cover topics such as mechanism of action, dosage regimen, adverse reactions, drug interactions, toxicity profiles, among other information of clinical relevance. The work comprises evidence-based studies, providing a valuable resource for analyzing, prescribing and monitoring patients being treated for Alzheimer’s disease. Written by experts with solid professional experience, this book will appeal to pharmacologists, geriatricians, neurologists, psychiatrists, biomedical clinicians, and other healthcare professionals. 1. Introduction Gustavo Alves Andrade dos Santos 2. Principles of Pharmacology in Dementia Francisco Assis Carvalho Vale, Judith Thomas Tayra, Carina Tellaroli Spedo 3. The Viability of Treatment Conditioned to the Pathophysiology of Alzheimer’s Disease Fabricio Ferreira de Oliveira 4. The Use of Esterase Inhibitors Gustavo Alves Andrade dos Santos, Carolina Witchmichen Penteado Schmidt, Karina Pedrotti Forlenza 5. Pharmacology of NMDA (N-methyl-D-aspartate) receptor antagonists in Alzheimer’s Disease Carolina Witchmichen Penteado Schmidt 6. Supportive Pharmacological Treatment Kalu Mormino Otoni, Karla Bruna Nogueira Torres Mormino, Sandna Larissa Freitas dos Santos, Maria Liliane Luciano Pereira 7. Herbal Medicines and Supplements Eduardo Carit 8. Emergency Situations Milena Carvalho Libardi, GuilhermeRiccioppo Rodrigues, Rui Kleber Martins Filho 9. Relationships between Treatment and Clinical Evaluations Paulo Pardi, Gustavo Alves Andrade dos Santos 10. New Perspectives for Treatment in Alzheimer’s Disease Jlia Cunha Loureiro, Marcos Vasconcelos Pais, Luiz Fernando de Almeida Lima e Silva, Orestes Vicente Forlenza
