Description
Dedication Acknowledgements Preface 1 Introduction Part I How drugs are discovered and developed in the pharmaceutical industry 2 Introduction to drugs and drug targets 3 Background to chemistry of small and large molecules 4 Laying the foundations- Drug discovery from antiquity to the twenty first century Part II The drug development pipeline – discovery to testing in humans 5 Drug discovery pipeline overview 6 Target discovery 7 Medicinal chemistry 8 Biotherapeutics 9 Screening for hits 10 Process chemistry and formulation 11 Preclinical development Part III The drug development pipeline – clinical trials to marketing authorisation 12 Clinical trials 13 Regulatory affairs and marketing approval 14 Diagnostics and personalized medicine 15 Putting it All Together: a drug development case history Part IV The Global Pharmaceuticals Business 16 Commercial aspects of drug development 17 Challenges and responses Part V Professional Interactions with the Drug Discovery Industry 18 Professional Interactions with the Drug Discovery Industry: Technology Transfer Executives 19 Recruitment Executives 20 Pharmaceutical translators and Interpreters Appendix 1 Further Reading Appendix 2 Glossary of terms
