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Preface… Table of Contents… Contributing Authors… 1. Using Lentiviral shRNA Delivery to Knock-Down Proteins in Cultured Neurons and In Vivo Kevin A. Wilkinson, Kirsty J. McMillan, Paul J. Banks, Ruth E. Carmichael, Yasuko Nakamura, Zafar I. Bashir, Peter J. Cullen, and Jeremy M. Henley 2. Synaptosomal Preparation and Its Application in Preclinical Studies Marco Feligioni, Lucia Buccarello, Kambiz Hassanzadeh, and Massimo Corbo 3. Assessing the Nanoscale Organization of Excitatory and Inhibitory Synapses using Recombinant Probes to Visualize Endogenous Synaptic Proteins Matteo Fossati, Marco Erreni, Martina Biagioni, and Alessandra Folci 4. Agonist-Induced Functional Analysis and Cell Sorting (aiFACS) to Select and Characterize Interneurons during Brain Development Julie Cazareth, Marielle Jarjat, Frderic Brau, Barbara Bardoni, and Thomas Maurin 5. A CRISPR/Cas9-Based Toolkit to Test Gain- and Loss-of-Gene Function in Brain Organoids Anne Le Digarcher, Cline Lemmers, Arnaud Monteil, Charles Hong, Annie Varrault, and Tristan Bouschet 6. Assessment of Adult Mouse Brain NeuroAnatomical Phenotypes using Quantitative and Precision Histology Stephan C. Collins and Binnaz Yalcin 7. Leveraging Microelectrode Array Technology for Phenotyping Stem Cell-Derived Neurodevelopmental Disease Models Shan Wang, Eline van Hugte, Ummi Ciptasari, and Nael Nadif Kasri 8. Humanized Chimeric Mouse Models to Study Human Neural Development and Pathogenesis of Brain Diseases Camille Thiberge, Maria Llach Pou, Aline Vitrac, Uwe Maskos, and Isabelle Cloz-Tayarani 9. In Vivo Manipulations to Correct for Behavioral Phenotypes in Cognitive Disorder Mouse Models Chun-Lei Zhang, Mattia Aime, and Yann Humeau 10. Assessing Dyadic Social Interactions in Rodent Models of Neurodevelopmental Disorders Sara Schiavi, Antonia Manduca, Emilia Carbone, Valeria Buzzelli, and Viviana Trezza 11. Central and Peripheral Explorations by Metabolomics to Study Neurodevelopmental Disorders Alexandra Bourdin-Pintueles, Laurent Galineau, Antoine Lefvre, Lydie Nadal-Desbarats, Sylvie Mavel, and Patrick Emond 12. Genetic Engineering of Non-Human Primates Models for Studying Neurodevelopmental Disorders Rahul Suresh, Platon Megagiannis, Hong Chen, Rogier Landman, Jitendra Sharma, and Yang Zhou Subject Index List…
