Description
While there are a number of books on the market that deal with neuronal mechanisms and targets, the proposed book will be the only one to cover the vascular aspects of CNS trauma. The contributing authors will present basic mechanisms, explain cutting-edge experimental models and techniques, and provide several clinical chapters that provide treating physicians with some insight on the cases that they see in the ICU. The table of contents is diverse and comprehensive with chapters on molecular mechanisms, physiology, pharmacology, stem cells, genomics and proteomics, in vivo MRI and PET, as well as the clinical management of vascular parameters. Part I: Molecular Mechanisms 1. CNS Barriers in Neurotrauma Adam Chodobski, Brian J. Zink, and Joanna Szmydynger-Chodobska 2. Mechanisms of Cerebral Edema Leading to Early Seizures after Traumatic Brain Injury Philip H. Iffland II, Gerald G. Grant and Damir Janigro 3. Human Cerebral Blood Flow and Traumatic Brain Injury David A. Hovda and Thomas C. Glenn 4. Gliovascular Targets in Traumatic CNS Injury Arjun Khanna, Brian P Walcott, Kristopher T Kahle, Volodymyr Gerzanich, J. Marc Simard 5. Neurovascular Responses to Traumatic Brain Injury Josephine Lok, Ken Arai, Shu-zhen Guo, Wendy Leung, Takakuni Maki, Deepti Navaratna, Klaus van Leyen, Changhong Xing, and Eng H. Lo 6. The Effects of Intravascular Coagulation and Microthrombosis on Cerebral Perfusion after Brain Trauma Monisha A. Kumar, Doug H. Smith, and Sherman C. Stein 7. Barriers to Drug Delivery for Brain Trauma Robert S. B. Clark 8. Angiogenesis and Functional Recovery after Traumatic Brain Injury Yanlu Zhang, Ye Xiong, Asim Mahmood, Zheng Gang Zhang, and Michael Chopp 9. Vascular Mechanisms in Spinal Cord Injury Theo Hagg 10. Neurovascular Mechanisms of Ischemia Tolerance Against Brain Injury Kunjan R. Dave, John W. Thompson, Jake T. Neumann, Miguel A. Perez-Pinzon, Hung W. Lin 11. Stem Cells for Neurovascular Repair in CNS Trauma Mibel M. Pabn, Travis Dailey, Naoki Tajiri, Kazutaka Shinozuka, Hiroto Ishikawa, Sandra Acosta, Yuji Kaneko, Cesar V. Borlongan 12. Vascular Actions of Hypothermia in Brain Trauma W. Dalton Dietrich and Helen M. Bramlett Part II: Experimental Models and Methods 13. Vascular Responses in Rodent Models of Traumatic Brain Injury Xiaoshu Wang, Zhanyang Yu, Zhengbu Liao, Qi Liu, MingMing Ning, Xiaochuan Sun, Josephine M. Lok, Eng H. Lo, Xiaoying Wang 14. SAH Models: Review, New Modification, and Prospective Sheng Chen, Damon Klebe, Alexander Vakhmyanin, Mutsumi Fujii, John H. Zhang 15. Age and Sex Differences In Hemodynamics In a Large Animal Model of Brain Trauma William M. Armstead and Monica S. Vavilala 16. Neutrophils as Determinants of Vascular Stability in the Injured Spinal Cord Alpa Mahuvakar, Sang Mi Lee, Haoqian Zhang, and Linda J. Noble-Haeusslein 17. Blood Biomarkers for Acute CNS Insults: Traumatic Brain Injury and Stroke Olena Glushakova, Stefania Mondello, Ronald L. Hayes 18. Biomaterials for CNS Injury Myron Spector and Teck Chuan Lim 19. Isolated Blood Vessel Models for Studying Trauma Eugene V. Golanov Part III: Clinical Challenges and Opportunities 20. Managing Edema and Intracranial Pressure in the Intensive Care Unit Brian Cummings, Phoebe H. Yager, Sarah A. Murphy, Brian Kalish, Chetan Bhupali, Rebecca Bell, Zenab Mansoor, Natan Noviski, and Michael J. Whalen 21. Surgical Management of Traumatic Brain Edema Takeshi Maeda, Tatsuro Kawamata, Atsuo Yoshino, Yoichi Katayama 22. Optimizing Hemodynamics in the Clinical Setting Jose Alberto Toranzo and Claudia S. Robertson, 23. Cerebrovascular Autoregulation and Monitoring of Cerebrovascular Reactivity Philip M. Lewis, Marek Czosnyka, Piotr Smielewski, John D. Pickard 24. Cerebrovascular Responses after Pediatric Traumatic Brain Injury Steven Shein, Nikki Ferguson, and Michael J. Bell 25. Subdural Hematoma in Non-Accidental Head Injury Jennifer C. Munoz Pareja, Josephine Lok, Natan Noviski, Ann-Christine Duhaime 26. Blood Genomics after Brain Ischemia, Hemorrhage, and Trauma Da Zhi Liu, Glen C Jickling, Boryana Stamova, Xinhua Zhan, Bradley P Ander and Frank R Sharp 27. Molecular Biomarkers in Neurocritical Care – The Next Frontier Sherry H-Y Chou and MingMing Ning 28. Bedside Monitoring of Vascular Mechanisms in CNS Trauma: The use of Near Infra-red Spectrpscopy (NIRS) and Transcranial Doppler (TCD) Sarah Murphy, Brian Cummings, David Boas and Natan Noviski 29. In vivo MRI and MRS of Cerebrovascular Function following Traumatic Brain Injury Chandler Sours, Rao P Gullapalli
