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Preface.. Table of Contents… Contributing Authors… 1. A 3D Biomimetic System for Testing Anticancer Drugs Sensitivity Miodrag Dragoj, Jasmina Stojkovska, Sofija Jovanovic Stojanov, Bojana Obradovic, and Milica PeSic 2. Patient-Derived Breast Cancer Tissue Cultures for Anti-Endocrine Drug Assays Giacomo Domenici, Gonalo Trindade, Marta F. Estrada, Ana Lusa Cartaxo, Paula M. Alves, Saudade Andr, and Catarina Brito 3. Co-Culture of Two Different Cell Lines in a Two-Layer Microfluidic Device Sharif M. Rahman, Elizabeth C. Martin, and Adam T. Melvin 4. Generation and Culture of Organotypic Breast Carcinoma Spheroids for the Study of Drug Response in a 3D Microfluidic Device Hamidreza Aboulkheyr Es, Amir Reza Aref, and Majid Ebrahimi Warkiani 5. A Methodological Workflow to Analyze Synthetic Lethality and Drug Synergism in Cancer Cells Johann Gout, Elodie Roger, Alexander Kleger, and Lukas Perkhofer 6. Establishment of In Vivo Acquired Resistance to Chemotherapy via Individual Dose Escalation Treatment Regime Karen T. Barker and Orli Yogev 7. A Label Retaining System to Capture Slow Cycling Cancer Cells Isabel Puig and Hctor G. Palmer 8. A Fast and Furious Liquid Biopsy Assay to Monitor Targeted Therapy Resistance Chiara Nicolazzo and Paola Gazzaniga 9. Assessment of Tumor Heterogeneity in High-Grade Serous Ovarian Cancer: Mass Cytometry to Understand the Complex Tumor Biology Luca Pasquini, Roberta Riccioni, and Eleonora Petrucci 10. Analysis of Transcriptomic Data Generated from Drug Treated Cancer Cell Line Swarnima Kushwaha, Sudeshna Mukherjee, Rajdeep Chowdhury, and Shibasish Chowdhury 11. Simultaneous Mapping of Enhancers and Enhancer Rearrangements with Paired-End H3K27ac ChIP-seq Israel Antman, Ester Davis, Shahd Abu-Kamel, Merav Hecht, and Yotam Drier 12. Identification of Drug Resistance Mechanisms using Genome-Wide CRISPR-Cas9 Screens Graham MacLeod, Nishani Rajakulendran, and Stephane Angers 13. RNA Sequencing Data Analysis on the Maser Platform and the Tag-Count Comparison-Graphical User Interface Kenta Ujifuku, Yoichi Morofuji, and Hiroshi Masumoto 14. Dissecting the Epigenomic Driving Drug Resistance by ATAC-Seq Francesca de Nicola, Giacomo Corleone, and Frauke Goeman 15. Polygenomic Interrogation of Drug Resistance Genes Robert J. Autry 16. Analysis of ER-phagy in Cancer Drug Resistance Sandhya Chipurupalli, Vincenzo Desiderio, and Nirmal Robinson 17. Drug Target Prediction using Context-Specific Metabolic Models Reconstructed from rFastcormics Tamara Bintener, Maria Pires Pacheco, Ali Kishk, Jeff Didier, and Thomas Sauter Subject Index List…
