Description
Airways inflammation is a complex biological phenomenon resulting from the recruitment and activation of numerous cell types. Airways inflammation contributes to the pathophysiology of airways disease. An understanding of the mechanisms that regulate inflammatory cell function is essential for the development of novel anti-inflammatory drugs for the treatment of common respiratory diseases such as asthma and COPD. This book provides a collection of valuable reviews on the major inflammatory cells involved in airways disease and examines the pharmacology of current anti-inflammatory drugs used in the treatment of airways disease. Moreover, an insight into the development of emerging drug therapies is also highlighted. This book is a must for the library of any researcher or clinician interested in the pathophysiology of airways disease. Pathological spectrum of airway inflammation.- Role of basophils in airways inflammation.- Platelets.- Neutrophils.- Eosinophils in asthma.- Fibroblasts and myofibroblasts.- Airway macrophages and dendritic cells.- Contribution of endothelial cells to airway inflammation.- Airway epithelial cells.- Airway smooth muscle cells.- Drugs that reduce airways inflammation.- T cells in the lung.
