Description
Als eines der ersten Bcher auf diesem Gebiet stellt dieses Werk eine komplette bersicht ber die kombinatorische Chemie dar – geschrieben von Experten und Erfindern dieser Technik. Es wird dem Chemiker helfen, Zeit und Geld zu sparen, indem ihm hier die Hintergrundinformationen der kombinatorischen Technik bereitgestellt werden zur Synthese von Tausenden oder Millionen von Verbindungen innerhalb kurzer Zeit. Stephen R. Wilson is Professor of Chemistry at New York University. He is also founder and President of Sphere Biosystems, Inc., in New Jersey, a biotech company based on fullerene combinatorial chemistry technology. Anthony W. Czarnik is Senior Director of Chemistry at IRORI Quantum Microchemistry in La Jolla, California, and formerly Director of BioOrganic Chemistry at Parke-Davis Pharmaceutical Research. Partial table of contents: Parallel Organic Synthesis Using Parke-Davis Diversomer Technology (S. DeWitt & A. Czarnik). Polymer-Supported Synthesis of Organic Compounds and Libraries (M. Kurth). Macro Beads as Microreactors: New Solid- Phase Synthesis Methodology (W. Rapp). Combinatorial Libraries in Solution: Polyfunctionalized Core Molecules (E. Wintner & J. Rebek). Solid-Phase Methods in Combinatorial Chemistry (I. Sucholeiki). Combinatorial Synthesis Exploiting Multiple-Component Condensations, Microchip Encoding, and Resin Capture (R. Armstrong, et al.). Indexed Combinatorial Libraries: Nonoligomeric Chemical Diversity for the Discovery of Novel Enzyme Inhibitors (M. Pirrung, et al.). Combinatorial Libraries of Peptides, Proteins, and Antibodies Using Biological Systems (S. Benkovic, et al.). Index.
