Description
Contents 1. Chapter 1: Drug Development in Psychiatry: The Long and Winding Road from Chance Discovery to Rational Development Author: Sheldon H. Preskorn 2. Chapter 2: The History of Drug Development in Psychiatry: A Lesson in Serendipity Author: Abhishek Wadhwa, MD* (Corresponding author) 3. Chapter 3: The Evolving Role of Animal Models in the Discovery and Development of Novel Treatments for Psychiatric Disorders Author: Laura Teal, Shalonda Ingram, Michael Bubser, Elliott McClure and Carrie K. Jones* (Corresponding author) 4. Chapter 4: Discovery and Development of Monoamine Transporter Ligands Author: Dr Mortensen* and Dr. Aggarwal* (*Corresponding authors) 5. Chapter 5: Drug Development for New Psychiatric Drug Therapies Author: M. Lynn Crismon (Corresponding author), Janet Walkow, Roger Sommi 6. Chapter 6: Post-Approval Research in Drug Development: Priorities and Practices Author: David Williamson (Corresponding author), Jack Sheehan, and Ella Daly 7. Chapter 7: Discovery of new transmitter systems and hence new drug targets Author: Tiffany Schwasinger-Schmidt (Corresponding author) and Sheldon Preskorn 8. Chapter 8: Reverse engineering drugs Author: Tiffany Schwasinger-Schmidt (Corresponding author) and Sheldon Preskorn 9. Chapter 9: Back to the Future of Neuropsychopharmacology Author: Anton Bespalov (Corresponding author), Marcel van Gaalen, Thomas Steckler 10. Chapter 10: Targeted Treatments for Fragile X Syndrome Author: Devon Johnson MD (Corresponding author), Courtney Clark BS, Randi Hagerman MD 11. Chapter 11: The Difficult Path to the Discovery of Novel Treatments in Psychiatric Disorders Diseases Author: Valentin K. Gribkoff* and Leonard K. Kaczmarek* (*Corresponding authors) 12. Chapter 12: Biomarkers in Psychiatric Drug Development: From Precision Medicine to Novel Therapeutics Author: Rudy Lozano Carreon, M.D., Ana Maria Rivas-Grajales, M.D., Nicholas Murphy, Ph.D., Sanjay J. Mathew, M.D., Manish K. Jha, M.B.B.S. (Corresponding author) 13. The role of fMRI in drug development: an update Author: Owen Carmichael (Corresponding author) 14. Monoamine Oxidase B (MAO-B): A Target for Rational Drug Development in Schizophrenia Using PET Imaging as an Example Author: Kankana Nisha Aji, Jeffrey H. Meyer, Pablo M. Rusjan , Romina Mizrahi (Corresponding author) 15. Genomics in Treatment Development Author: Yogesh Dwivedi, PhD and Richard C. Shelton, MD (Corresponding author) 16. Increased Inflammation and Treatment of Depression: from Resistance to Reuse, Repurposing and Redesign Author: Jennifer C. Felger, Ph.D., M.S. (Corresponding author) 17. Experimental medicine approaches in early phase CNS drug development Author: Brett A. English (Corresponding author) and Larry Ereshefsky
